NCT05492955Completed
Implementation of a Combination Intervention for Sustainable Blood Pressure Control
Implementation of a Combination Intervention for Sustainable Blood Pressure Control in KwaZulu-Natal, South Africa (IMPACT-BP)
Source: ClinicalTrials.gov · Last updated 12 Mar 2026
Brief summary (registry, in English)
This is a randomized clinical trial intended to identify the optimal strategy of blood pressure management in rural South Africa using Community Health Workers (CHWs) in conjunction with in-home BP monitoring among adults.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 774 (actual)
- First submitted
- 5 Aug 2022
- Start date
- 30 Nov 2022
- Primary completion date
- 18 Dec 2024
- Lead sponsor
- Brigham and Women's Hospital
- Diseases
- High blood pressure
- NCT number
- NCT05492955
What you commit to
- Study type: Interventional
- Participants enrolled: 774
- From 30 Nov 2022 to the primary completion date, 18 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current use of at least 3 different anti-hypertensive therapies at full dose.
Other illness
- Severe, symptomatic hypertension with a measured blood pressure \> 180/110 mmHg.
Lab values
- Known, advanced chronic kidney disease. GFR \< 60 ml/min/1.73 m2.
Other
- Pregnant or breast-feeding women.
- Planning to move within the next 24 months.
Who the study is looking for
- Age greater than 18 years old
- Residing in uMkhanyakude District in northern KwaZulu-Natal in an area that is served by a CHW.
- Elevated blood pressure (blood pressure \> 140/90 mmHg) on two measurements.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Africa Health Research Institute (AHRI) Coordinator of this site? Confirm its status | Mtubatuba | South Africa | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.