NCT05497414Completed
Neuroimaging Sleep and Mood in Depression
Identifying Brain Dynamics Underlying Sleep and Mood in Depression
Source: ClinicalTrials.gov · Last updated 27 Jul 2026
Brief summary (registry, in English)
This study will investigate how sleep and mood are related in patients with depression and in healthy controls. It will use MRI-based measures of brain function to determine how neural systems are modulated by sleep and sleep deprivation, and its links to mood in depression.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 81 (actual)
- First submitted
- 24 Feb 2022
- Start date
- 31 Jan 2022
- Primary completion date
- 15 Mar 2024
- Lead sponsor
- Boston University Charles River Campus
- Diseases
- Depression
- NCT number
- NCT05497414
What you commit to
- Study type: Interventional
- Participants enrolled: 81
- From 31 Jan 2022 to the primary completion date, 15 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Must have no history of major head trauma
- No lifetime history of schizophrenia or any other psychosis disorder, substantial intellectual disability, bipolar disorder, post-traumatic stress disorder or obsessive compulsive disorder
- Must not be taking medications that significantly affect sleep, psychiatric function, blood/vascular function, or anti-inflammatory medications (other than minor NSAID use).
Other
- Must not have ferrous metal implanted in head or body
- Must not have implanted electronic devices (e.g., pacemaker, neurostimulator)
- Must not be pregnant, suspect they are pregnant, or seeking to become pregnant
- Must not be claustrophobic
- Must have no piercings or jewelry that cannot be removed
- Weight less than 250 pounds
- No alcohol or substance abuse or dependence within the past 6 months
- No significant personality dysfunction
- Must not indicate significant suicide risk.
Who the study is looking for
- Adult aged 18-80
- \- Current diagnosis of major depressive disorder
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Boston University Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.