NCT05497687Completed
Strength-building Lifestyle-integrated Intervention
A Strength-building Lifestyle-integrated Intervention for Tackling Double Burden of Sarcopenic Patients With Coronary Artery Disease: A Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 7 Dec 2023
Brief summary (registry, in English)
This study aims to 1) develop a strength-building lifestyle-integrated intervention for sarcopenic CAD patients and to 2) examine the feasibility and 3) preliminary effects of this intervention on skeletal muscle mass, muscle strength, physical performance, cardiac-related functional status and health-related quality of life (HRQoL), psychological distress, major adverse cardiovascular and cerebral events (MACCE) and hospital readmission rates
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 3 Aug 2022
- Start date
- 22 Sept 2022
- Primary completion date
- 31 Aug 2023
- Lead sponsor
- The University of Hong Kong
- Diseases
- Coronary artery disease
- NCT number
- NCT05497687
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 22 Sept 2022 to the primary completion date, 31 Aug 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Physical limitations precluding exercise training, with any contraindication for exercise, any terminal or unstable conditions (e.g., malignant arrhythmia, severe aortic stenosis, cancer);
- Admitted or recently completed a structured cardiac rehabilitation program within the past 6 months
Other
- Cannot read Chinese or with impaired cognition (Abbreviated Mental Test score ≤6) or communication;
- A pacemaker or implantable cardioverter defibrillator precluding the use of bioelectrical impedance analysis for body composition assessment;
Who the study is looking for
- Chinese adults with a confirmed diagnosis of coronary artery disease (CAD);
- Age ≥60 years or older;
- Presence of sarcopenia according to the diagnostic criteria defined by the Asian Working Group for Sarcopenia1: low skeletal muscle mass (measuring the appendicular skeletal muscle mass with bioelectrical impedance analysis: \<7.0 kg/m2 for men and \<5.7 kg/m2 for women), accompanied by low muscle strength (handgrip strength \<28 kg for men and \<18 kg for women);
- Free from ischemic symptoms when performing activities of daily living;
- Living in the community.
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The School of Nursing Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.