NCT05500989Recruiting
PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis
Source: ClinicalTrials.gov · Last updated 5 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Pregnancy is considered a cardiovascular (CV) stress test, and complicated pregnancies are associated with an increased risk for cardiovascular disease (CVD) later in life. Moreover, it is known that often the pregnancy induced CV adaptation does not resolve completely after a short postpartum (PP) period and it is not clear whether these induced changes will resolve over a longer period of time (i.e. in the upcoming months/years after delivery). Understanding the cardiac adaptation during pregnancy and the reversal process in the postpartum period, as well as the factors that influence this these processes, may provide us not only insight in this mechanism, but may help us in identifying factors that may be target points for modification.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 226 (estimated)
- First submitted
- 5 May 2022
- Start date
- 1 Nov 2016
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Maastricht University Medical Center
- NCT number
- NCT05500989
What you commit to
- Study type: Observational
- Planned participants: 226
- From 1 Nov 2016 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Controls: Pre-existing chronic hypertension treated with antihypertensive medication or autoimmune disorder.
Other illness
- Allergy or intolerance to glyceryl trinitrate, betablockers or iodinated contrast media.
Other
- Women who do not want to be informed about the results of the tests, or women who do not want their general practitioner and specialist(s) to be informed about the test results
Who the study is looking for
- Women aged ≥ 18 years
- Controls: Women with an uncomplicated pregnancy at the moment of inclusion (i.e no foetal or maternal placental complications, such as pregnancy induced hypertension, preeclampsia or HELLP-syndrome, or small for gestational birth infancies)
- Cases: Women diagnosed with a preeclamptic pregnancy at the moment of inclusion
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Maastricht University Medical Center+ (MUMC+) Coordinator of this site? Confirm its status | Maastricht | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.