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NCT05505019Recruiting

Targeting Apathy With Music in Parkinson's Disease

The Role of a Personalized Music Intervention Towards Alleviating Apathy in Parkinson's Disease

Source: ClinicalTrials.gov · Last updated 23 Mar 2026

Brief summary (registry, in English)

Parkinson's Disease (PD) is often accompanied by non-motor symptoms that make treatment more difficult. One such symptom is apathy (lack of motivation and emotion). There are no treatments for apathy in PD, and this remains a major unmet need in PD patients. One possible way to target apathy in PD patients is listening to music, which has been shown to help improve apathy in older adults. Little work has explored the mechanism in which music targets apathy. Thus, the goal of this study is to understand how music listening can impact the brain towards decreasing apathy in PD patients.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
50 (estimated)
First submitted
19 Jul 2022
Start date
Feb 2022
Primary completion date
Jul 2026
Lead sponsor
University of British Columbia
NCT number
NCT05505019

What you commit to

  • Study type: Interventional
  • Planned participants: 50
  • From Feb 2022 to the primary completion date, Jul 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Participants with atypical Parkinsonism (eg. Progressive supranuclear palsy, multiple system atrophy, drug induced, etc.)
  • Participants who have gone through specific injuries/brain surgery (eg. an injury where a piece of metal lodged in the eye or orbit)

Other illness

  • Epilepsy
  • Other neurological disease/complications (eg. myopathy, stroke, brain lesion, MS)
  • Significant cognitive impairment (MoCa \<21)
  • Participants with metal/medical implants, including any of the following: artificial heart valve, brain aneurysm clip, electrical stimulators, ear or eye implant, implanted drug infusion pump, coil, catheter, or filter in any blood vessel, orthopedic hardware such as artificial joint, plate, and/or screws, other metallic prostheses, shrapnel, bullets, or other metal fragments, surgery or tattoos, including tattooed eyeliner, in the last six weeks, cardiac pacemaker, wires or defibrillator, or ferromagnetic aneurysm clip)

Other

  • Moderate depression (Beck's Depression Inventory \>20)
  • Severe/multiple head trauma(s)

Who the study is looking for

  • \- Clinical diagnosis of Parkinson's Disease following MDS Parkinson's disease criteria

Age in the registry: 40 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Djavad Mowafghian Centre for Brain Health
Coordinator of this site? Confirm its status
VancouverCanadaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.