NCT05507749Active, not recruiting
Cyroablation for Pulmonary Vein Isolation Alone in Patients With Early Persistent AF Assessed by Continuous Monitoring
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
This study aimed to evaluate the efficacy of Cryoablation in patients with early persistent atrial fibrillation as a first index procedure using continuous cardiac rhythm monitoring.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 130 (actual)
- First submitted
- 8 Aug 2022
- Start date
- 27 Nov 2020
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Seoul National University Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT05507749
What you commit to
- Study type: Interventional
- Participants enrolled: 130
- From 27 Nov 2020 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous ablation procedure or surgery for atrial fibrillation
- Contraindication to chronic anticoagulation therapy or heparin
Other illness
- A percutaneous coronary intervention or myocardial infarction ≤3 months
- A stroke or transient ischemic attack ≤6 months
- Uncontrolled hypertension, untreated hypothyroidism or hyperthyroidism
- Requirement for dialysis due to terminal renal failure
Lab values
- Severe left ventricular dysfuncion (left ventricle ejection fraction \< 30%)
Other
- Long-standing persistent atrial fibrillation more than 3 years
- Sinus rhythm at enrollment
- Recurrent sinus rhythm after electrical cardioversion
- Documented left atrial diameter \>50 mm from parasternal long-axis view
- Planned cardiovascular intervention
- Mental or physical inability to participate in the study
- Participation in another randomized clinical trial
Who the study is looking for
- Drug refractory symptomatic persistent atrial fibrillation diagnosed within 3 years
- Either two conditions
- atrial fibrillation episode lasting longer than 7 days, but less than 3 years documented by consecutive electrocardiogram recordings of 100% atrial fibrillation greater than 7 days apart or
- atrial fibrillation episode requiring electrical or pharmacological cardioversion after 24 hours of atrial fibrillation documented by continuous recording
- Willing to comply with study requirements and give informed consent to participate in this clinical study
Age in the registry: 20 years to 79 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National university Hostpital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.