NCT05510167Recruiting
Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF
Impact of Post-ablation Alcohol Intake on Arrhythmia Recurrence, Quality of Life and Cognition in Patients With Atrial Fibrillation
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
Earlier studies have shown a dose-dependent relationship between alcohol intake and incident atrial fibrillation (AF) as well as a causal link with several risk factors for AF such as hypertension, obesity and sleep apnea. However, the effect of drinking (alcohol) on post-ablation outcome such as arrhythmia recurrence, quality of life (QoL) and cognitive function in AF patients is unclear. Therefore, we aim to find the answer for a very frequently asked question, "is it safe to continue drinking alcohol (at the pre-ablation level) following catheter ablation OR should the intake be reduced for better outcome?", in this randomized trial.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 184 (estimated)
- First submitted
- 15 Aug 2022
- Start date
- 22 Aug 2022
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- Texas Cardiac Arrhythmia Research Foundation
- Diseases
- Atrial fibrillation
- NCT number
- NCT05510167
What you commit to
- Study type: Interventional
- Planned participants: 184
- From 22 Aug 2022 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Psychiatric conditions
- Patients with established dementia
Lab values
- LVEF \<35%
Other
- Binge drinkers (alcohol dependence)
- Non-drinkers
- MoCA score ≤ 17 on Montreal Cognitive Assessment (MoCA)
- Medically unstable patients (acute/unstable or poorly controlled problems that would demand focused, relatively urgent or emergent medical attention)
- Unwilling for alcohol-abstinence
- Long-standing persistence AF
- Patient under legal protection
- Pregnancy
Who the study is looking for
- AF patients that regularly consume \>5 alcoholic drink (\*12 g of pure alcohol/drink)/week
- Paroxysmal or persistent AF
- First catheter ablation History of alcohol-induced arrhythmia
- Willing to sign the written informed consent
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Texas Cardiac Arrhythmia Institute, St. David's Medical Center Coordinator of this site? Confirm its status | Austin | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.