NCT05511597Completed
Split-belt Treadmill Training for Freezing of Gait in Parkinson's Disease
Turning Around Freezing: Effect of Split-belt Treadmill Training on Daily-life Turning-related Freezing of Gait in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
A split-belt treadmill (SBT) is a treadmill with two belts, whereby each leg can be driven at a different speed. Previous work by the investigators showed that one session of SBT training improved turning while multi-tasking and reduced FOG in PwPD tested in the laboratory. However, subsequent work raises questions as to whether treadmill improvements following repeated SBT training generalize to overground situations in the long term. Therefore, in this study, the investigators will perform a four-week SBT intervention with added practice of everyday turning scenarios (SBT+CP) or placebo exercise (SBT+PL), and study its effects on FOG in both the laboratory and at home.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 26 (actual)
- First submitted
- 18 Aug 2022
- Start date
- 16 Dec 2022
- Primary completion date
- 31 Oct 2025
- Lead sponsor
- KU Leuven
- Diseases
- Parkinson disease
- NCT number
- NCT05511597
What you commit to
- Study type: Interventional
- Participants enrolled: 26
- From 16 Dec 2022 to the primary completion date, 31 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Be between 40 - 90 years of age
- Have a diagnosis of Parkinson's disease
- Be able to walk for 10 min without an aid
- Be able to follow and understand the oral instructions of the investigator
- Have a disease stage of I to IV (while ON-medication)
- Have had no change in your Parkinson's medication in the past month (or to your deep brain stimulator if applicable) and also no planned changes in medication over the next 4 months
- Have at least about 1 "freezing" episode per day (based on the New Freezing of Gait Questionnaire: N-FOG)
- Not participating in another clinical trial
- Have no acute joint disease
- Not have any other condition that affects your walking pattern or prevents you from completing all study tasks
- Have not undergone major surgery or hospitalization in the last 3 months
- No substance abuse
- No depressive disorder or other apathetic disorder that precludes daily exercise
Age in the registry: 40 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Movement and Rehabilitation Sciences (FaBeR) Coordinator of this site? Confirm its status | Leuven | Belgium | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.