NCT05513794Completed
Prospective Study for Neuromelanin Image Analysis
Prospective Data Collect Study for Development of Neurimelanin Image Analysis System
Source: ClinicalTrials.gov · Last updated 28 Jul 2025
Brief summary (registry, in English)
In order to develop an image analysis system that automatically detects and quantifies neuromelanin, this study aims to construct a database of a wide sample by collecting brain MRI neuromelanin images prospectively.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 220 (actual)
- First submitted
- 22 Aug 2022
- Start date
- 2 Nov 2022
- Primary completion date
- 2 Jul 2024
- Lead sponsor
- Heuron Inc.
- Diseases
- Parkinson disease
- NCT number
- NCT05513794
What you commit to
- Study type: Interventional
- Participants enrolled: 220
- From 2 Nov 2022 to the primary completion date, 2 Jul 2024
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient with a history of claustrophobia and mental illness;
- Patient with a history of central nervous system disease or cognitive disorder
- Patient with a history of claustrophobia and mental illness;
Other
- Patient with metallic substances in the body
- Any female subject who is likely to be pregnant who does not agree to contraception in a medically permitted manner during this clinical trial period
- Pregnant or lactating women
- Other cases where the investigator judged that it is difficult to participate in the study;
- Healthy volunteer group
- Patient with metallic substances in the body
- Any female subject who is likely to be pregnant who does not agree to contraception in a medically permitted manner during this clinical trial period
- Pregnant or lactating women
- Other cases where the investigator judged that it is difficult to participate in the study;
Who the study is looking for
- Adults over 19 years old
- Those who have clinically shown Parkinson's symptoms such as tremor, Rigidity, Bradykinesa and gait disturbance and are scheduled to take MRI scans
- Dopamine transporter imaging shows a significant decrease in visual dopamine intake
- A person who can read and understand the description and informed consent form
- Upon hearing and fully understanding the detailed explanation of this clinical trial, a person who has voluntarily decided to participate and agreed in writing to comply with the precautions
- Adults over 19 years old
- A person who has no family history or diagnostic history of movement disorders;
- A person with a score of 8 or higher on the CCSIT(cross cultural smell identification test)
- A person with a score of 27 or higher on the MMSE Test
- No Parkinson's symptoms on a neurological examination
- Upon hearing and fully understanding the detailed explanation of this clinical trial, a person who has voluntarily decided to participate and agreed in writing to comply with the precautions
Criteria the registry did not label
- Parkinsin group
Age in the registry: 19 years to - · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yong-in Severance Hospital, Yonsei University Health System Coordinator of this site? Confirm its status | Gyeonggi-do | South Korea | Unknown status |
| Inje University Sanggye Paik Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Severance Hospital, Yonsei University Health System Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.