NCT05527574Completed
Home-based Interventions for FrAilty preveNTion in AdultS With DIabeTes and Chronic Kidney Disease
Development of an Innovative Home-based Strategy for FrAilty preveNTion in AdultT With dIabetes and Chronic Kidney Disease (FANTASTIC)
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
One of the most common problems in people with diabetes (DM) and chronic kidney disease (CKD) is the high frequency of other coinciding medical conditions such as osteoporosis and frailty. Frailty in particular is very common in adults with DM and CKD and it can result in significant muscle weakness which can result in increasing difficulties with performing activities of daily life (ADL). This can lead to an increase risk for falls, bone fractures and increasing hospitalization. The investigators have showed that adults with DM and CKD who have frailty use hospital services more frequently, have reduced quality of life and difficulties with performing their ADLs1. There is some evidence that early screening for frailty and lifestyle interventions that focus on healthier eating and physical activity can help prevent frailty from getting worse. The study purpose is to develop and test a home-based lifestyle intervention program focused on optimizing diet and the ability to perform your ADLs in adults with DM and CKD. The goal of this program is to ensure that adults with DM can live healthier lives within the community.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 120 (actual)
- First submitted
- 25 Aug 2022
- Start date
- 30 Nov 2019
- Primary completion date
- 29 Dec 2025
- Lead sponsor
- University of Alberta
- Diseases
- Chronic kidney disease, Type 2 diabetes
- NCT number
- NCT05527574
What you commit to
- Study type: Interventional
- Participants enrolled: 120
- From 30 Nov 2019 to the primary completion date, 29 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Recent history of bone fracture in the last 12 months
- History of skeletal muscular disorders which precludes the ability to perform resistance exercises (e.g., moderate to severe osteoarthritis that prevents walking, bending and/or sit to stand or wheelchair dependent)
- Dialysis (hemodialysis or peritoneal dialysis) as treatment of kidney disease
Other
- Functional and cognitive impairments (MMSE scores\<24)
- Severe, permanent vision loss.
- Pregnant women
Who the study is looking for
- Adults (50-85 years)
- Clinically Diagnosed with diabetes (Type 2) and stage 1-IV CKD (Glomerular Filtration - Rate (GFR) 10-89 ml/min/1.73m2).
Age in the registry: 50 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Diabetic Nephropathy Prevention Clinic - Alberta Kidney Care - North Coordinator of this site? Confirm its status | Edmonton | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.