NCT05529264Recruiting
Human Intracranial Electrophysiology
Source: ClinicalTrials.gov · Last updated 15 Jan 2026
Brief summary (registry, in English)
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have electrodes implanted in the brain and/or have electrodes on the scalp. Additionally, this study will recruit normal and online controls (participants who do not have epilepsy). Participants will be asked to participate in 1 to 2 (30-90 minutes) daily sessions designed to test aspects of human cognition such as memory, speech, language, feeling, movement, attention, sound perception, and emotions. Generally, this will involve working on a computer, looking at pictures or watching videos, and answering questions. Additionally, participants may be asked to be hooked up to additional equipment such as eye tracker, electrical stimulator, heart rate monitor, sweat monitor or other non-invasive equipment. The overall aim of this study is to use human intracranial electrophysiology (the recording of the electrical activity of the human brain) to study localization and function of the human brain.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 175 (estimated)
- First submitted
- 22 Aug 2022
- Start date
- 17 Jan 2023
- Primary completion date
- 1 Aug 2027
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Diseases
- Epilepsy
- NCT number
- NCT05529264
What you commit to
- Study type: Interventional
- Planned participants: 175
- From 17 Jan 2023 to the primary completion date, 1 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Patients with Intracranial EEG: Inclusion Criteria
- Patients must be age 18 years or older. There is no upper age limit.
- Patients must have a diagnosis of refractory epilepsy undergoing intracranial EEG recording for clinical purposes.
- Patients with Intracranial EEG: Exclusion Criteria
- Patient has additional neurological condition (such as stroke or dementia) or a psychiatric condition (such as active psychosis or suicidal ideation) and are deemed inappropriate for the study
- Patients are not able to provide informed consent for any reason (e.g. encephalopathic, experiencing a seizure)
- Patients with Scalp EEG: Inclusion Criteria
- Patients must be age 18 years or older. There is no upper age limit.
- Patients must have a probable diagnosis of epilepsy.
- Patients with Scalp EEG: Exclusion Criteria
- Patient has additional neurological condition (such as stroke or dementia) or a psychiatric condition (such as active psychosis or suicidal ideation) and are deemed inappropriate for the study
- Patients are not able to provide informed consent for any reason (e.g. encephalopathic, experiencing a seizure)
- Normal Controls: Inclusion Criteria
- Participants must be age 18 years or older. There is no upper age limit.
- Participants must be able to provide informed consent for themselves.
- Normal Controls: Exclusion Criteria
- Determined not to be appropriate normal control for the study population
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dartmouth Hitchcock Medical Center Coordinator of this site? Confirm its status | Lebanon | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.