NCT05531461Recruiting
Cognition and Imaging With Tigertriever
COGNITIVE Study- Cognition and Imaging With Tigertriever
Source: ClinicalTrials.gov · Last updated 9 Oct 2026
Brief summary (registry, in English)
The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 424 (estimated)
- First submitted
- 4 Sept 2022
- Start date
- 28 Oct 2024
- Primary completion date
- Nov 2026
- Lead sponsor
- Rapid Medical
- Diseases
- Stroke
- NCT number
- NCT05531461
What you commit to
- Study type: Observational
- Planned participants: 424
- From 28 Oct 2024 to the primary completion date, Nov 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of any other IA recanalization device prior to the Tigertriever in the target vessel, including aspiration catheter.
- Prior hemorrhage, stroke, thrombolysis, and/or endovascular therapy in the last 3 months.
Other illness
- Evidence of acute brain hemorrhage on CT and/or MRI at admission.
- Pre-stroke diagnosed dementia and/or prescribed cholinesterase inhibitors.
- Pre-stroke diagnosed and/or currently treated major depression.
- Pre-stroke learning or intellectual disability.
Other
- Probable cerebral amyloid angiopathy.
- Anticipated inability to obtain 6-month follow-up assessments.
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Who the study is looking for
- Patients admitted with large vessel occlusion (LVO) and treated with the Tigertriever, as indicated per the approved IFU.
- Tigertriever was used as the first line treatment in the target vessel.
- A signed informed consent.
- Age 18-75 years (inclusive).
- No known significant pre-stroke disability (pre-stroke mRS 0 or 1).
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Corewell Health Research Institute Coordinator of this site? Confirm its status | Grand Rapids | United States | Recruiting |
| University of California Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
| Westchester Medical Center Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| University of California Irvine Coordinator of this site? Confirm its status | Orange | United States | Recruiting |
| The Hospital of the University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Montefiore Medical Center The University Hospital for Albert Einstein College of Medicine Coordinator of this site? Confirm its status | The Bronx | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.