NCT05532904Completed
Multidisciplinary Day-hospital Versus Waiting List Management of Post-COVID-19 Persistent Symptoms (ECHAP-COVID)
Evaluation and Comparison of Multidisciplinary Day-hospital Versus Waiting List Management of Persistent Symptoms After an Acute Episode of COVID-19
Source: ClinicalTrials.gov · Last updated 5 Mar 2026
Brief summary (registry, in English)
After an acute episode of COVID-19, many patients experience persistent or recurrent symptoms with substantial impairment of their quality of life. The most common symptoms are fatigue, dyspnea, cognitive impairment and pain, but symptoms of all types have been reported. The heterogeneity of symptoms and their potential pathophysiology makes individualized and multidisciplinary management essential. The primary objective of this study is to evaluate the change in quality of life at 6 months in patients with persistent symptoms after an acute episode of COVID-19 after 6 weeks of personalized multidisciplinary outpatient management versus usual care.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 12 Jul 2022
- Start date
- 18 Jan 2023
- Primary completion date
- 13 Jun 2025
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT05532904
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From 18 Jan 2023 to the primary completion date, 13 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Having had an initial episode of symptomatic COVID-19 according to one of the following criteria:
- SARS-Cov-2 PCR +
- SARS-Cov-2 + antigenic test
- SARS-Cov-2 + serology
- Prolonged anosmia/ageusia of sudden onset
- Typical chest CT scan
- Still having at least one of the initial symptoms and possibly new symptoms including fatigue, dyspnea, cognitive impairment or pain beyond 4 weeks after the onset of the acute phase of the disease.
- These initial and persistent symptoms are not better explained by another diagnosis not known to be related to Covid-19.
- These symptoms are the cause of an alteration in quality of life and global functioning deemed significant by the patient.
- Having an indication to either supervised exercise and / or cognitive behavior therapy and / or cognitive remediation Exclusion Criteria
- Medical emergency requiring management not compatible with research
- Neuropsychiatric disorder likely to alter cognitive functions, prior to the Covid-19 episode
- Medical contraindication to exercise training such as pericarditis or progressive myocarditis
- Patient under state medical assistance
- Patient who does not speak French
- Pregnancy in progress
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôtel Dieu Hospital Coordinator of this site? Confirm its status | Paris | France | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.