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NCT05533515Completed

Circulating Tumour Cells as Biomarkers to Predict Prostate Cancer Metastasis for Treatment Stratification of Cancer

Circulating Tumour Cells as Biomarkers to Predict Prostate Cancer Metastasis for Treatment Stratification of Localised Cancer

Source: ClinicalTrials.gov · Last updated 19 Aug 2025

Brief summary (registry, in English)

The goal of this study is to establish the value of Circulating Tumour Cell (CTC) positivity in predicting post-RP treatment failure, including BCR and new lesions detected by cancer imaging. We plan to recruit participants who will undergo Radical Prostatectomy (RP). Participants will have their blood samples taken just before surgery and 3 months after the surgery to test for CTCs. Then participants will be followed-up for cancer progression information at 3 month intervals for the first year then yearly intervals after that. Their PSA will be observed over time.

Status (registry)
Completed
Study type
Observational
Enrollment
330 (actual)
First submitted
5 Sept 2022
Start date
8 Feb 2022
Primary completion date
5 Mar 2024
Lead sponsor
Queen Mary University of London
NCT number
NCT05533515

What you commit to

  • Study type: Observational
  • Participants enrolled: 330
  • From 8 Feb 2022 to the primary completion date, 5 Mar 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • With other co-occurring cancers

Other

  • Neo-adjuvant ADT
  • Adjuvant ADT

Who the study is looking for

  • High/High intermediate risk non-metastatic risk localised PCa based on the EAU stratification system
  • Scheduled for robot-assisted RP
  • Informed consent

Age in the registry: 18 years to 99 years · Sex: Male · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University College London Hospitals
Coordinator of this site? Confirm its status
LondonUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.