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NCT05535894Completed

Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer

Endoscopic Ultrasound-guided Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer

Source: ClinicalTrials.gov · Last updated 28 Apr 2026

Brief summary (registry, in English)

This study aims to evaluate the EUS-RFA in terms of efficacy for pain management and improvement in quality-of-life parameters for patients with advanced inoperable pancreatic cancer. The primary objectives of this study are to 1) evaluate the utility of EUS-RFA for pain control and improvement in quality-of-life parameters for patients with advanced pancreatic cancer; 2) to measure the reduction of analgesic medications' requirements in patients affected by inoperable pancreatic cancer.

Status (registry)
Completed
Study type
Observational
Enrollment
19 (actual)
First submitted
7 Sept 2022
Start date
10 Aug 2022
Primary completion date
30 Aug 2025
Lead sponsor
West Virginia University
NCT number
NCT05535894

What you commit to

  • Study type: Observational
  • Participants enrolled: 19
  • From 10 Aug 2022 to the primary completion date, 30 Aug 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Evidence of concurrent infection;

Other illness

  • Surgically resectable pancreatic cancer;
  • Abdominal pain with etiology other than pancreatic malignancy;

Lab values

  • Patients with irreversible coagulopathy international normalized ratio \>1.5 or platelet count \<50,000/mm3),

Other

  • Patients who are not willing to give informed consent or agree to participate in the study
  • Patients with a preliminary diagnosis of adenocarcinoma are not possible established with intraprocedural at EUS-guided FNA.

Who the study is looking for

  • Diagnosis of pancreatic cancer based on clinical, radiological, or pathological assessment;
  • Referred for abdominal and/or back pain due to pancreatic cancer;
  • No prior history of RFA;
  • Cancer pain unresponsive to the WHO 3-step analgesic ladder;
  • Willingness to consent to participate in the study.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Shailendra Singh
Coordinator of this site? Confirm its status
MorgantownUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.