NCT05538351Active, not recruiting
A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney Injury
Source: ClinicalTrials.gov · Last updated 5 Dec 2025
Brief summary (registry, in English)
Acute Kidney Injury (AKI) is the sudden and recent reduction in kidney function. This can be detected by measuring a rise in blood creatinine level or from a reduction in urine. Reasons for developing AKI, include dehydration, low blood pressure, medication and infection. When the kidneys stop working, there can be a build-up of toxins and fluid. It is extremely important to identify a patient's fluid status as too little can cause further damage to the kidneys and too much can be harmful. Assessment is varied and often inaccurate and there needs to be a standard approach to fluid assessment.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 120 (estimated)
- First submitted
- 8 Sept 2022
- Start date
- 9 Sept 2022
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- University of Hertfordshire
- Diseases
- High blood pressure
- NCT number
- NCT05538351
What you commit to
- Study type: Observational
- Planned participants: 120
- From 9 Sept 2022 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are receiving end of Life (EoL) care.
Other illness
- Patients who have kidney failure requiring dialysis or who are being conservatively managed.
- The patient has acute coronary syndrome
Lab values
- There is no baseline creatinine.
Other
- Patients who have a pacemaker as this interferes with bioimpedance (WS1+3).
- The patient has acquired an AKI 72 hours after admission to hospital.
Who the study is looking for
- Workstream 1 and 3 (phase 3):
- Patients who will be included in the study will be Adult patients (over 18 years old) identified as having an acute kidney injury (AKI) within 72 hours of admission to hospital.
- Workstream 2:
- Experts in fluid assessment (Doctors, Nurses and AHPs). Persons included will be experts in their field of practice and have a recognised expertise in fluid assessment.
- Workstream 3:
- Phase 1: Experts in fluid assessment (Doctors, Nurses and AHPs). Phase 2: Staff nurses currently working on a clinical ward.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| East and North Hertfordshire NHS Trust, Lister Hospital Coordinator of this site? Confirm its status | Stevenage | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.