NCT05546931Recruiting
Mobile Health Program for Rural Hypertension
Multilevel Mobile Health Program to Improve Rural Hypertension
Source: ClinicalTrials.gov · Last updated 19 Nov 2025
Brief summary (registry, in English)
Hypertension (HTN) is the leading modifiable cause of cardiovascular disease. Rural individuals experience challenges of the rural health divide: geographic distance from providers, social isolation, limited social resources, and high rates of low health literacy. This study evaluates a home-based blood pressure monitoring (HBPM) program that provides longitudinal health education, empathic guidance, monitoring, and adaptable patient-centered coaching to rural individuals. Participants in this study will be randomized to receive (1) HBPM with the intervention; or (2) the control, consisting of HBPM and a smartphone with a general health application (WebMD).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 334 (estimated)
- First submitted
- 15 Sept 2022
- Start date
- 4 Sept 2023
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Pittsburgh
- Diseases
- High blood pressure
- NCT number
- NCT05546931
What you commit to
- Study type: Interventional
- Planned participants: 334
- From 4 Sept 2023 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Heart failure necessitating hospital admission ≤3 months prior to study inclusion;
- Acute coronary syndrome (defined as at least 2 of the following: chest pain, ischemic electrocardiographic changes, or troponin ≥0.1 ng/mL) ≤3 months prior to study inclusion;
- Planned major surgery, cardiovascular or non-cardiovascular;
Other illness
- Presence of non-cardiovascular conditions likely to be fatal within 12 months (e.g., cancer);
Other
- Pregnancy or planned pregnancy within 12 months;
- Inability to comprehend the study protocol, defined by failing 3 times to answer correctly a set of questions during consent;
- Institutionalized status (e.g., nursing home, incarceration);
- Inability to operate a smartphone or HBPM device due to sensory or neurocognitive deficit.
Who the study is looking for
- History of uncontrolled hypertension, identified from the electronic health record problem list and an average systolic BP 140-199 or diastolic BP 90-119 mm Hg at 2 ambulatory visits, one of which is within 6 months of study entry
- Residence in one of 48 counties categorized as rural by the Center for Rural Pennsylvania;
- English-speaking at level appropriate for informed consent and study participation;
- No plans to relocate from the area within 12 months of enrollment.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Medical Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
Related publications
- Effect of Health Literacy on use of a Virtual Coach to Promote Home Blood Pressure Monitoring.J Clin Hypertens (Greenwich) · 2026 · PMID 42324623
This page is information, not medical advice. Discuss any trial with your doctor.