NCT05548413Recruiting
Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies
Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies in Patients With Heart Failure
Source: ClinicalTrials.gov · Last updated 5 May 2026
Brief summary (registry, in English)
People with heart failure who do not take their medications as prescribed are at high risk of complications leading to hospitalization, death and poor quality of life. In the proposed intervention, nurses will use easy-to-understand language to coach patients and their care partners to help them work together and build skills to overcome their individual barriers to adherence in order to 1) improve and sustain patient medication adherence; 2) reduce hospitalization; 3) improve quality of life. If effective, this intervention will support long-term medication adherence, thus reducing hospitalizations related to heart failure and quality of life.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 328 (estimated)
- First submitted
- 16 Sept 2022
- Start date
- 4 Jan 2023
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Jia-Rong Wu
- Diseases
- Heart failure
- NCT number
- NCT05548413
What you commit to
- Study type: Interventional
- Planned participants: 328
- From 4 Jan 2023 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- currently or have received any similar self-care intervention recently in the past year
Other illness
- cognitive impairment as indicated by having difficulties to understand and give informed consent
- co-existing end-stage renal disease or terminal illness such as advanced malignancy, or any other condition with less than 1-year life expectancy
- psychotic illness
- cognitive impairment as indicated by having difficulties to understand and give informed consent
- coexisting terminal illness
Other
- a recent hospitalization within 3 months of study enrollment
- current alcohol dependence or other substance abuse
- inability to speak English or other communication barrier
- non-English speaking or any other communication barrier
Who the study is looking for
- confirmed diagnosis of heart failure (HF), either systolic or diastolic HF
- ave suboptimal medication adherence
- have a care partner (CP) (either spouse, daughter/son, partner, other relative, friend) who is identified by the patient as the person most involved in HF care
- willingness to have a CP be involved in their medication taking
- have undergone evaluation of HF and prescribed stable doses of HF medications for at least 3 months
- live in a setting where the patient is responsible for their ow medication administration
- willing to use the SimpleMed+ (i.e., an electronic pillbox to measure objective medication adherence)
- availability by phone
- unpaid family member, friend, partner, or other relation who is involved in the patients' care at least 3 times a week, designated by the patient
- willing to receive interventions with the patient together
- 18 years of age or older
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jia-Rong Wu Coordinator of this site? Confirm its status | Lexington | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.