NCT05551104RecruitingPhase 3
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension: A Randomized Control Trial (SCARPH)
Source: ClinicalTrials.gov · Last updated 4 Feb 2026
Brief summary (registry, in English)
The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 19 Sept 2022
- Start date
- 8 May 2023
- Primary completion date
- Dec 2027
- Lead sponsor
- Loma Linda University
- Diseases
- High blood pressure
- NCT number
- NCT05551104
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 500
- From 8 May 2023 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema
Other
- Contraindication to either Nifedipine or Labetalol
- HR \<60 or \>110
- Native language other than English or Spanish
Who the study is looking for
- Female
- Women who develop postpartum hypertension\* after delivery of the placenta or chronic hypertensive postpartum women who require medication for blood pressure control.
- Postpartum hypertension requiring treatment are defined as systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than or equal to 90mmHg on at least 2 occasions at least 4 hours apart, or systolic blood pressure greater than or equal to 160mmHg or diastolic blood pressure greater than 110mmHg sustained for more than 15 minutes.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Loma Linda University Health Coordinator of this site? Confirm its status | Loma Linda | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.