NCT05551182CompletedPhase 3
Nicergoline Use in Dysphagia Patients
The Study of Efficacy on Low Dose Nicergoline in Dysphagia Patients Compares With High Dose Nicergoline.
Source: ClinicalTrials.gov · Last updated 4 Mar 2026
Brief summary (registry, in English)
Dysphagia is a complication in patient with stroke, Parkinson's disease or dementia that can lead to aspiration pneumonia. This study aimed to investigate dysphagia improvement after treatment with nicergoline low dose and high dose, the relationship between nicergoline dose and clinical improvements, side effect of nicergoline and simulation optimal nicergoline dose in dysphagia improvement.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 92 (actual)
- First submitted
- 19 Sept 2022
- Start date
- 1 Jan 2023
- Primary completion date
- 31 Jul 2025
- Lead sponsor
- Phramongkutklao College of Medicine and Hospital
- Diseases
- Stroke, Parkinson disease
- NCT number
- NCT05551182
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 92
- From 1 Jan 2023 to the primary completion date, 31 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- On antiplatelet \> 1 drug (ex. dual antiplatelet)
- Laryngopharynx surgery
Other illness
- Allergy to gentamicin or components
- Impair hepatic function including child puge B, C or active hepatitis
- Brainstem stroke
- Parkinson plus syndrome: PSP, MSA, DLB, etc
- Advanced cancer or other medical conditions
- Active bleeding
Lab values
- Chronic gout or hyperuricemia \> 8 mg/dL
Other
- On anticoagulants including Heparin, Enoxaparin, Fondaparinux, Warfarin, Dabigatran, Apixaban, Rivaroxaban and Edoxaban
- On ACE-I or Dopaminergic agent 2 months or less
- Chronic dyspepsia
- CrCl \< 30 ml/min
- Bed ridden
- SBP\<100 or DBP 60 mmHg
- HR\<50/min
- Pregnancy or lactation
- Known of poor compliance for any treatments
Who the study is looking for
- Age greater than or equal to 20 years
- Stroke (post events at least 2 months), Parkinson's disease and dementia patients who have dysphagia symptom
- Do not take nicergoline prior recruit 2 weeks
- Continue current medications
- Consent to join
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Phramongkutklao Hospital Coordinator of this site? Confirm its status | Ratchathewi | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.