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NCT05553873Recruiting

Evaluation of Inflammatory Markers in ph Negative Myeloproliferative Neoplasms: Impact on Outcome and Response to Therapy. Multicenter Retro-prospective Observational Study. The INFLA-ME (INFLAmmation in Myeloproliferative Disease) Study.

Source: ClinicalTrials.gov · Last updated 2 Jan 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This study aims to observe inflammatory biomarkers and their trend over the history of the disease in patients suffering from MPN Ph negative; it also wants to identify any correlations between the aforementioned biomarkers and disease outcomes, considering first of all the occurrence of thrombo-haemorrhagic events and the evolution in the accelerated / blast phase of the disease, shedding light on new tools that can potentially guarantee a prompt and better risk stratification

Status (registry)
Recruiting
Study type
Observational
Enrollment
500 (estimated)
First submitted
21 Sept 2022
Start date
8 Sept 2022
Primary completion date
Dec 2026
Lead sponsor
University of Milano Bicocca
NCT number
NCT05553873

What you commit to

  • Study type: Observational
  • Planned participants: 500
  • From 8 Sept 2022 to the primary completion date, Dec 2026
  • 11 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Life expectancy of less than 6 months
  • Accelerated phase myelofibrosis or MPN with signs of leukemic evolution

Who the study is looking for

  • Age ≥ 18 years at the time of diagnosis of MPN Ph negative
  • Diagnosis of PV, ET, PMF or post PV and post ET MF, according to current WHO or IWG-MRT criteria (diagnosis since 2000)
  • Obtaining informed consent

Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (11)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Azienda Ospedaliera Universitaria Consorziale Policlinico
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BariItalyRecruiting
Policlinico Sant'Orsola-Malpighi
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BolognaItalyRecruiting
ASST Spedali Civili di Brescia
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BresciaItalyRecruiting
Policlinico Vittorio Emanuele
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CataniaItalyRecruiting
Ospedale Universitario Federico II
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NaplesItalyRecruiting
Policlinico Umberto I - Università La Sapienza
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RomaItalyRecruiting
Azienda Ospedaliera Universitaria Città della Salute e delle Scienza
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TorinoItalyRecruiting
Ospedale San Luigi di Orbassano - Ospedale Mauriziano
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TorinoItalyRecruiting
Azienda Ospedaliera Universitaria Friuli Centrale
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UdineItalyRecruiting
Azienda Ospedaliera Universitaria integrata
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VeronaItalyRecruiting
Ospedale Belcolle
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ViterboItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.