NCT05554224Recruiting
Integrated Multi-omics Data for Personalized Treatment of Obesity-associated Fatty Liver Disease
Integrated Multi-omics and Machine Learning-driven Personalized Treatment of Obesity-associated Fatty Liver Disease
Source: ClinicalTrials.gov · Last updated 13 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The investigators seek to analyze the samples provided by patients with obesity-associated fatty liver disease at the multi-omics level and to integrate the results with clinical information, genotypic variants, and factors influencing inter-organ crosstalk. The main aim is to improve the interpretation of fatty liver disease associated with obesity and diabetes by developing predictive models built with algorithms from artificial intelligence. The challenge is to decipher the flow of information by exploring contributing factors, proximate causes of regulatory defects, and maladaptive responses that may promote therapeutic approaches.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1104 (estimated)
- First submitted
- 21 Sept 2022
- Start date
- 25 Jun 2008
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Institut Investigacio Sanitaria Pere Virgili
- Diseases
- Obesity, Fatty liver disease (MASLD/MASH)
- NCT number
- NCT05554224
What you commit to
- Study type: Observational
- Planned participants: 1104
- From 25 Jun 2008 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Legal or illegal drug consumption, including alcohol.
Other illness
- Diagnosis of Hepatitis.
- Current cancer diagnosis or treatment.
- Clinical or analytical evidence of severe illness.
- Clinical or analytical evidence of infectious diseases.
- Clinical or analytical evidence of terminal illness.
Other
- Clinical or analytical evidence of chronic or acute inflammation.
Who the study is looking for
- Body mass index greater or equal to 40 kg/m\^2.
- Body mass index between 35 and 40 kg/m\^2 with high-risk comorbidities (diagnosis or treatment for hypertension, dyslipidemia, or type 2 diabetes mellitus).
- Positive psychiatric evaluation.
- Age greater or equal to 18 years old.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Universitari Sant Joan Coordinator of this site? Confirm its status | Reus | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.