NCT05556395Recruiting
Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline
Source: ClinicalTrials.gov · Last updated 4 Sept 2026
Brief summary (registry, in English)
The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 22 Sept 2022
- Start date
- 1 Apr 2022
- Primary completion date
- 1 Apr 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- Stroke, Alzheimer disease
- NCT number
- NCT05556395
What you commit to
- Study type: Observational
- Planned participants: 150
- From 1 Apr 2022 to the primary completion date, 1 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Inability to perform telephone-based cognitive assessments
Who the study is looking for
- Acute ischemic stroke demonstrated on an MRI scan that includes perfusion imaging with an exogenous contrast agent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins Hospital Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.