NCT05557864Recruiting
Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease
Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease; Udall Project 2 Aims 1 & 2
Source: ClinicalTrials.gov · Last updated 26 Jan 2026
Brief summary (registry, in English)
This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant to dopamine replacement therapy, these experiments will likely have major impact on clinical practice by providing a potential strategy to these medically intractable symptoms.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 12 Sept 2022
- Start date
- 25 Aug 2016
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of Minnesota
- Diseases
- Parkinson disease
- NCT number
- NCT05557864
What you commit to
- Study type: Interventional
- Planned participants: 24
- From 25 Aug 2016 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- history of musculoskeletal disorders that significantly affect movement of the upper or lower limbs
- other significant neurological disorder
- history of dementia or cognitive impairment as found with UBACC (or MacCAT-CR)
Other
- post-operative complications or adverse effects
Who the study is looking for
- diagnosis of idiopathic PD
- have undergone neurosurgery to implant deep brain stimulators in the globus pallidus (GP DBS) or subthalamic nucleus (STN)
- Existing 7T brain imagery
Age in the registry: 21 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Minnesota Coordinator of this site? Confirm its status | Minneapolis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.