NCT05558111Recruiting
The Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Neuroimaging Study of Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain activity of lower urinary tract function in neobladder patients is still unclear.The aim of this study is to explore the brain activity of urination intention and self-controlled urination behavior in patients with orthotopic sigmoid neobladder by task-state functional magnetic resonance imaging (fMRI).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 24 Sept 2022
- Start date
- Jun 2022
- Primary completion date
- Dec 2028
- Lead sponsor
- Zhujiang Hospital
- Diseases
- Bladder cancer
- NCT number
- NCT05558111
What you commit to
- Study type: Observational
- Planned participants: 40
- From Jun 2022 to the primary completion date, Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Claustrophobia or carrying metal implants that are not suitable for fMRI examination;
Other illness
- History of bladder radiotherapy;
- History of prostate cancer;
- Suffering from diseases affecting abdominal pressure;
- History of abnormal brain anatomy, craniocerebral surgery, craniocerebral tumor, and craniocerebral radiotherapy;
- History of mental disorders, Parkinson's disease, Alzheimer's disease, epilepsy, cerebral infarction, cerebral hemorrhage;
- Diseases affecting lower urinary tract function (such as spinal cord injury, diabetic peripheral neuropathy, etc.);
- Other conditions that were not suitable for inclusion according to the investigator's judgment.
Other
- Urethral stricture;
- Refusing to sign the informed consent form for clinical projects;
Who the study is looking for
- Being right-handed;
- 3 months or more after operation;
- No contraindications to fMIR examination;
- Voluntarily sign informed consent.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhujiang Hospital of Southern Medical University Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.