NCT05558241Active, not recruiting
Micro-UltraSound In Cancer - Active Surveillance
Micro-UltraSound In Cancer - Active Surveillance (MUSIC-AS)
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 210 (actual)
- First submitted
- 23 Sept 2022
- Start date
- Nov 2022
- Primary completion date
- Aug 2026
- Lead sponsor
- University of Alberta
- Diseases
- Prostate cancer
- NCT number
- NCT05558241
What you commit to
- Study type: Interventional
- Participants enrolled: 210
- From Nov 2022 to the primary completion date, Aug 2026
- 6 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Men who cannot undergo a prostate MRI
- Men who cannot undergo a prostate biopsy
Who the study is looking for
- Adult men with Gleason Grade Group 1 prostate cancer managed by active surveillance who require a confirmatory prostate biopsy
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kipnes Urology Centre - Kaye Edmonton Clinic Coordinator of this site? Confirm its status | Edmonton | Canada | Unknown status |
| CIUSSS du Nord-de-L'Ile-De-Montreal Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| University of British Columbia Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
| University Hospital Centre Zagreb Coordinator of this site? Confirm its status | Zagreb | Croatia | Unknown status |
| Humanitas Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| University of California Los Angeles, Department of Urology Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.