NCT05558384Completed
Influence of Adiposity on IGF-1 and Fitness Response to Exercise in Cancer Survivors
The Influence of Excess Adiposity on Cardiorespiratory, Insulin-like Growth Factor, and Metabolic Responses to a Standardized Aerobic Exercise Program in Cancer Survivors
Source: ClinicalTrials.gov · Last updated 24 Feb 2025
Brief summary (registry, in English)
This is a pilot feasibility study of an investigation of the influence of excess adiposity on cardiorespiratory fitness (CRF), insulin-like growth factor-1 (IGF-1), and metabolic responses to a standardized aerobic exercise program in cancer survivors. This investigation attempts to isolate the influence of adiposity on these responses. We will enroll overweight, obese, and normal weight cancer survivors with a primary diagnosis of breast, prostate, or colorectal cancer who have completed all cancer-related treatment. Participants will engage in a 15-week aerobic exercise intervention with pre- and post-intervention assessments.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 12 (actual)
- First submitted
- 19 Sept 2022
- Start date
- 22 Mar 2023
- Primary completion date
- 1 Oct 2024
- Lead sponsor
- University of Colorado, Denver
- Diseases
- Obesity
- NCT number
- NCT05558384
What you commit to
- Study type: Interventional
- Participants enrolled: 12
- From 22 Mar 2023 to the primary completion date, 1 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of a secondary active cancer diagnosis or metastatic disease
- Any current cancer treatment (including hormonal treatment) or planned cancer treatment in the next 5 months
- Any significant metabolic condition, such as diabetes. Individuals with pre-diabetes or metabolic syndrome will not be excluded, but this information will be recorded.
- Any medical condition that would impact the safety of, or participation in, an exercise program or exercise testing, including:
- Orthopedic conditions such as advanced osteoarthritis, mobility-limiting amputations or chronic injuries, or mobility-limiting acute orthopedic injuries
- Advanced rheumatoid arthritis or chronic widespread pain conditions such as fibromyalgia
- Pulmonary conditions such as chronic obstructive pulmonary disease, emphysema, or interstitial lung disease
- Known cardiovascular disease, uncontrolled hypertension, or new cardiac event within the past 6 months
Other
- Greater than 100 min of self-reported regular exercise per week
- BMI \< 18.5 (underweight)
Who the study is looking for
- Primary cancer diagnosis of breast, prostate, or colorectal cancer
- Completion of all cancer-related treatment \> than 6 months prior and \< 5 years prior to enrollment
- Ability and willingness to participate in a supervised exercise program
- All participants will be required to obtain a signed physician clearance to participate in exercise form prior to enrollment
Age in the registry: 21 years to 79 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Hospital Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.