NCT05559749Active, not recruiting
Collaborative Care for Anxiety and Depression in Epilepsy
Collaborative Care to Improve Quality of Life for Anxiety and Depression in Epilepsy
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
This is a randomized effectiveness/implementation trial comparing a 24-week neurology-based collaborative care intervention to usual neurology care among 60 adults with epilepsy.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 26 Sept 2022
- Start date
- 4 May 2023
- Primary completion date
- Mar 2027
- Lead sponsor
- Wake Forest University Health Sciences
- Diseases
- Epilepsy
- NCT number
- NCT05559749
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 4 May 2023 to the primary completion date, Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- receiving ongoing psychotherapy OR
- Unstable drug or alcohol abuse
- For the third Aim (sustainability supplement: intervention only care delivery exploratory study supplement) - the Participants meeting the following criteria may participate
Other illness
- Comorbid medical condition with life expectancy less than 6 months
- History of past suicide attempt and:
- History of suicide attempt in the past year and:
- currently prescribed 2 or more psychotropic medications for psychiatric indication (not merely as a hypnotic) AND not felt to be a good candidate for collaborative care based on the judgement of the investigators
- individuals who meet the above INC-EXC criteria except rather than having a diagnosis of Epilepsy; they have a diagnosis of functional neurological disorder with seizures
Other
- Current participation in another treatment of intervention study
- Cognitive limitations precluding completion of Anxiety and Depression self-report instruments on paper, electronically, or by interview
- Not a good candidate for collaborative care due to:
- Active ongoing treatment by a psychiatrist
- Active suicidal ideation
- has seen a psychiatrist in the past year
- individuals who meet the above INC-EXC criteria and have completed the Control Arm of a collaborative care research study - NCT05559749 - NCT05353452 or
- individuals who meet the above INC-EXC criteria and receive clinical neurological care at Atrium Health Wake Forest Baptist
Who the study is looking for
- Provision of signed and dated Informed Consent Form
- Stated willingness to comply with all study procedures
- Males and Females; Age \>= 18 years
- \* Diagnosis of epilepsy: Epilepsy diagnosis based on neurology clinician impression or EEG findings
- Anxiety or Depression symptoms
- Receiving clinical neurological care at Atrium Health
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Wake Forest University Health Sciences Coordinator of this site? Confirm its status | Winston-Salem | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.