NCT05560087Completed
Association of PeRiODontal Disease and gUt Microbiome With Coronary artEry Disease (PRODUCE Study)
Source: ClinicalTrials.gov · Last updated 1 Jan 2025
Brief summary (registry, in English)
The purpose of this study is to explore the relationship between periodontal disease and coronary artery disease through changes in the gut microbiome. In addition, the investigators aim to find possible periodontal pathogens that have association with cardiovascular disease.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 450 (actual)
- First submitted
- 19 Sept 2022
- Start date
- 1 Jul 2022
- Primary completion date
- 5 Dec 2024
- Lead sponsor
- Yonsei University
- Diseases
- Coronary artery disease
- NCT number
- NCT05560087
What you commit to
- Study type: Observational
- Participants enrolled: 450
- From 1 Jul 2022 to the primary completion date, 5 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- prior gastrointestinal surgery within 1 year
Other illness
- active malignancy
- active autoimmune disease
- active inflammatory bowel disease
- Active liver disease or liver cirrhosis
Lab values
- chronic kidney disease (eGFR\<30, or on dialysis)
Other
- Patients with prosthetic valve
- pregnancy
- consistent use of probiotics
Who the study is looking for
- -Patients aged from 19 to 80 years who underwent invasive coronary angiography for clinical necessity, with informed consent
Age in the registry: 19 years to 80 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yonsei University Health System, Severance Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.