NCT05561062CompletedPhase 2
Atorvastatin in Patients With Ulcerative Colitis
Combination of Atorvastatin and Mesalazine to Enhance Anti-inflammatory Effects and Attenuates Progression of Ulcerative Colitis
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood. Statins exert numerous pleiotropic effects including anti-inflammatory, antioxidant properties, endothelial function improvement, and immunomodulation independent of their basic lipid-lowering property.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 27 Sept 2022
- Start date
- 1 Jan 2023
- Primary completion date
- 1 Mar 2024
- Lead sponsor
- Tanta University
- Diseases
- Ulcerative colitis
- NCT number
- NCT05561062
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 50
- From 1 Jan 2023 to the primary completion date, 1 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients taking rectal or systemic steroids
- Patients taking immunosuppressives or biological therapies
Other illness
- Colorectal cancer patients
Other
- Breastfeeding
- Significant liver and kidney function abnormalities
- Patients with severe UC
Who the study is looking for
- Age ≥ 18 years
- Both male and female will be included
- Negative pregnancy test and effective contraception
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Medicine, Mansoura University Coordinator of this site? Confirm its status | Al Mansurah | Egypt | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.