NCT05562193Completed
Exercise and Pain in CCS
Exercise Intervention Coupled With Standard Post-cancer Directed Treatment Care to Reduce Chronic Pain in Childhood Cancer Survivors Who Have Completed Cancer-directed Therapy Less Than One Year
Source: ClinicalTrials.gov · Last updated 14 May 2025
Brief summary (registry, in English)
The purpose of this study is to demonstrate that integration of exercise intervention into standard post-cancer directed treatment care will improve patient reported pain, decrease the need for medications to manage chronic pain and improve functional and psychosocial outcomes in survivors of cancers in children and adolescents. Our central hypothesis is that integration of exercise interventions into standard post-cancer directed treatment care will be acceptable and feasible while improving patients' pain, decreasing the cumulative dose of pain medication and improving patients' functional and psychosocial outcomes as compared to patients who only receive standard post-cancer directed treatment care.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 26 Sept 2022
- Start date
- 30 Sept 2022
- Primary completion date
- 11 Mar 2025
- Lead sponsor
- Milton S. Hershey Medical Center
- Diseases
- Childhood cancers
- NCT number
- NCT05562193
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 30 Sept 2022 to the primary completion date, 11 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- CCS who have not completed all standard/planned cancer treatment and/or not in complete remission at the time of recruitment
- CCS who are \> 1-year post cancer therapy
- CCS who have history of refractory or recurrent cancer
Lab values
- CCS who have evidence in their medical record of an absolute contraindication to complete any of the physical assessments in their medical record. This exclusion criterion is at the oncologist's discretion when research staff will contact the medical oncologist via secure email or secure message through the electronic medical record for approval to approach their patients for the study and for medical clearance. The oncologists can update this information at any time during the study if there is evidence of an absolute contraindication to complete any of the physical assessments.
Age
- CCS who are \< 10 years old and \> 17 years old at the time of enrollment
Other
- CCS or their parent/legal guardian who are unable to speak, read, and understand the English language
- CCS who are unable to access and complete online questionnaires
Who the study is looking for
- Male and female CCS diagnosed with any type of cancer
- CCS who have completed all standard/planned cancer treatment and are stable at the time of recruitment
- CCS are \< 1-year post cancer therapy
- CCS who have chronic pain (pain will be self-reported by the participant, will have to be ≥1 on a scale of 10 and lasting for 3 months or longer)
- CCS who are age between 10 and 17 years old at the time of enrollment
- CCS who are and who are not non-ambulatory/wheelchair bound.
- CCS and parent/legal guardian must be able to speak, read and understand the English language
- CCS's parent or legal guardian must be able to provide and understand informed consent
- CCS must be able to provide and understand assent
- CCS must be able to attend three visits (baseline, 8 and 16-week follow-up) at the Penn State Health Children's Hospital
- CCS and parent/legal guardian must have access to a computer, smartphone or tablet
- Note: The agreement of the attending oncologist will be required for the participation of CCS eligible for this study.
Age in the registry: 10 years to 17 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penn State Health Children's Hospital Coordinator of this site? Confirm its status | Hershey | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.