NCT05562960Completed
Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP
Source: ClinicalTrials.gov · Last updated 22 Jul 2026
Brief summary (registry, in English)
Patient with amyotrophic lateral sclerosis (ALS) having anti-NRIP autoantibody showed titer-dependent detrimental Effects. Plasmapheresis might benefit this subgroup of patients via removal of anti-NRIP autoantibody
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 5 (actual)
- First submitted
- 28 Sept 2022
- Start date
- 1 May 2023
- Primary completion date
- 31 Mar 2025
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT05562960
What you commit to
- Study type: Interventional
- Participants enrolled: 5
- From 1 May 2023 to the primary completion date, 31 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Specific ALS subtypes, including primary lateral sclerosis, progressive muscular atrophy, flail arm syndrome, or flail leg syndrome.
Lab values
- Blood fibrinogen level less than 50 mg/dl.
Other
- Patients without plasma anti-NRIP autoantibody.
- Patients requiring permanent ventilator support for ALS progression.
- Not able to receive plasmapheresis or trial-related examinations.
- Under pregnancy.
Who the study is looking for
- Patients with amyotrophic lateral sclerosis (ALS) at the age more than 20 years and having plasma anti-NRIP autoantibody.
- Agree to receive plasmapheresis intervention.
- Agree to participate in the trial and receive serial examinations and follow up.
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.