NCT05565313Completed
Predicting Radiological Extranodal Extension in Oropharyngeal Carcinoma Patients Using AI
Source: ClinicalTrials.gov · Last updated 9 Oct 2026
Brief summary (registry, in English)
Development and validation of a model that predicts rENE from radiological imaging using annotated / labeled scans by means of deep learning
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 900 (actual)
- First submitted
- 29 Sept 2022
- Start date
- 22 Mar 2022
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Maastricht Radiation Oncology
- Diseases
- Head and neck cancer
- NCT number
- NCT05565313
What you commit to
- Study type: Observational
- Participants enrolled: 900
- From 22 Mar 2022 to the primary completion date, 1 Aug 2026
- 3 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- removal of lymph node (LN) (excisional biopsy or neck dissection \[ND\]) prior to staging CT/MR scan
- no available imaging within 2 months prior to radiotherapy (RT)"
Who the study is looking for
- Non-metastatic (M0) node-positive HPV+ and HPV- oropharyngeal carcinoma
- Treated between 2008 to 2019
- Curative intent
- Radiation only or concurrent chemoradiation
- Modern treatment modality: IMRT / VMAT
- diagnostic/staging image scanning protocols available (contrast-enhanced CT with 2-3 mm slice thickness and/or MR with 3 mm slice thickness)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Princess Margaret Cancer Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Maastro Coordinator of this site? Confirm its status | Maastricht | Netherlands | Unknown status |
| Harvard Medical School and clinical faculty at Dana-Farber Cancer Institute/Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.