NCT05566483Recruiting
Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
Physiological Underpinnings of Post-Acute Sequelae of SARS CoV-2 ("Long COVID") and Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
Source: ClinicalTrials.gov · Last updated 4 Dec 2025
Brief summary (registry, in English)
The primary objectives of this study are to determine whether exercise training is an effective strategy for treatment of Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 30 Sept 2022
- Start date
- 1 Mar 2023
- Primary completion date
- 31 Oct 2027
- Lead sponsor
- University of Colorado, Denver
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT05566483
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 1 Mar 2023 to the primary completion date, 31 Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of cardiovascular/pulmonary disease prior to infection
Other illness
- COVID-related myocardial injury such as evidence of myocarditis
- Deep vein thrombosis/pulmonary embolism following COVID-19 infection
- Exercise intolerance resulting from conditions that are not related to cardiorespiratory or autonomic factors (e.g. osteoarthritis or other musculoskeletal diseases);
- Dependency of supplemental oxygen following COVID infection due to cardiovascular and/or pulmonary complications following acute COVID infection
Who the study is looking for
- Adults ≥18 years with documented history of COVID-19 infection and symptoms consistent with Long COVID lasting \>12 weeks after diagnosis.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Hospital Coordinator of this site? Confirm its status | Aurora | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.