NCT05568134Completed
Alternate Measures of Glucose During OGTT Testing for CFRD
Correlations Between CGM and Serum Glucose During OGTT Testing for CFRD
Source: ClinicalTrials.gov · Last updated 24 Feb 2025
Brief summary (registry, in English)
Although early detection and treatment of cystic fibrosis-related diabetes (CFRD) can lead to significant clinical improvements and prolong life, rates of screening are poor likely due to the burdensome nature of oral glucose tolerance testing (OGTT). The investigators propose to assess the feasibility and accuracy of two screening tools, continuous glucose monitoring (CGM) and a home OGTT kit (GTT@home). If this pilot study reveals acceptable accuracy of either device, this study will allow for future studies exploring home-based OGTT screening.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 14 (actual)
- First submitted
- 3 Oct 2022
- Start date
- 17 Jul 2023
- Primary completion date
- 13 Dec 2024
- Lead sponsor
- Children's Hospital of Philadelphia
- Diseases
- Cystic fibrosis
- NCT number
- NCT05568134
What you commit to
- Study type: Observational
- Participants enrolled: 14
- From 17 Jul 2023 to the primary completion date, 13 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- ≥ 10 years of age
- Fluency in written and spoken English as the GTT@Home is currently only available in English Exclusion Criteria: * Hospitalization or treatment with IV antibiotics or supraphysiologic glucocorticoids within 4 weeks
- Major medical or psychiatric disorders other than CF
- Use of medications known to impact the accuracy of the Dexcom G7 (hydroxyurea, \>2g acetaminophen per day)
- History of severe adhesive reactions that may lead to an inability to tolerate CGM wear
Age in the registry: 10 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital of Philadelphia Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.