NCT05568420Active, not recruiting
A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)
Investigation of the Potential Effects of Pharmacologic Agents on Young Onset- Colorectal Cancer
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
This study will collect biospecimens (including blood, tissue, and stool samples) and health information to create a database-a type of collection of information-for better understanding young onset colorectal cancer (YOCRC). The study will include both people with YOCRC and healthy people.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 41 (actual)
- First submitted
- 30 Sept 2022
- Start date
- Sept 2022
- Primary completion date
- Sept 2027
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Diseases
- Colorectal cancer
- NCT number
- NCT05568420
What you commit to
- Study type: Observational
- Participants enrolled: 41
- From Sept 2022 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of or prior treatment for cancer ≤ 5 years prior to registration. Exceptions include non-melanoma skin cancer, ductal carcinoma in situ, bladder carcinoma in situ, or carcinoma-in-situ of the cervix.
Other illness
- Known inherited cancer susceptibility gene
- History of inflammatory bowel disease
- Healthy Control Cohort:
Other
- CRC Cohort:
- Antibiotic use within 6 months of collection of stool for gut microbiome analysis s (only patients providing stool sample)
- Antibiotic use within 6 months of collection of stool for gut microbiome analysis (only patients providing stool sample)
- Colonoscopy for indications of IBD, anemia and/or genetic predisposition (only patients providing tissue sample).
Who the study is looking for
- CRC Cohort:
- 18-49 years old
- Histological or cytological diagnosis of colorectal adenocarcinoma
- Planned CRC resection biopsy, or colonoscopy ,including surveillance colonoscopies and/or have already undergone prior surgical resection, with tissue, including normal colonic mucosae distant from the malignant tumor (only patients providing tissue sample)
- Enrollment in IRB# 20-315, Young Onset Gastrointestinal Cancer Prospective Registry (Andrea Cercek, PI)
- Healthy Control Cohort:
- 18-49 years old at time of diagnosis
- Scheduled for standard-of-care colonoscopy at MSK
- Underwent surgical resection of a traumatic injury to the colon at Shaare Zedek Medical Center (SZMC)
Age in the registry: 18 years to 49 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Sloan-Kettering Cancer Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.