NCT05570578Completed
Effects of Transcranial Direct Current Stimulation (tDCS) on Brain Organization and Naming in Aphasic Patients.
Effects of Transcranial Direct Current Stimulation (tDCS) on Brain Organization and Naming
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) allows to induce, in a non-invasive way, a transient inhibitory or excitatory neuromodulation of a given cerebral region and to obtain a very focused cortical effect. Previous studies using HD-tDCS have shown the effectiveness of this stimulation technique for enhancing language recovery in patients with aphasia. However, language processes are not determined solely by local neural activity at a single site, but rather by the interaction between neural networks. This is because a large cortical network is involved in language processes and, therefore, the same language disorder may result from lesions at different locations in this network. The investigators hypothesize that anodal HD-tDCS will enhance neural interactions between language areas and, thereby, improve language processing and word learning. The investigators propose to carry out a study on chronic aphasic patients involving HD-tDCS of the Broca region (left inferior frontal gyrus) combined with a verb learning task.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 14 (actual)
- First submitted
- 4 Oct 2022
- Start date
- 24 Oct 2022
- Primary completion date
- 1 Feb 2026
- Lead sponsor
- Adrian Guggisberg
- Diseases
- Stroke
- NCT number
- NCT05570578
What you commit to
- Study type: Interventional
- Participants enrolled: 14
- From 24 Oct 2022 to the primary completion date, 1 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Contraindication to tDCS: pregnant women, patients with active implants such as pacemakers or cochlear implants, patients with one or more seizures, metal objects in the brain
- Occurrence of a new stroke during the study protocol.
Other
- Patients unable to understand the given information on the study and its objectives, or instructions for tasks performed.
- Impaired alertness or delirium
- Severe co-morbidity affecting speech
Who the study is looking for
- Ischemic or hemorrhagic stroke
- Presence of aphasia with difficulty finding words and/or naming objects/pictures
- ≥12 months post-stroke
- ≥ 18 years of age
- French-speaking
- Able to participate in 30-60 min therapeutic sessions (good concentration and understanding of the task and ability to follow instructions
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Division of Neurorehabilitation, University Hospital of Geneva Coordinator of this site? Confirm its status | Geneva | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.