NCT05571514Recruiting
Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis
Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis: Multicentre, Double-blind Randomized Versus Positive Comparator Study
Source: ClinicalTrials.gov · Last updated 2 Oct 2026
Brief summary (registry, in English)
Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality. Given potential side effects, hormone replacement therapy is no longer recommended for menopausal women with risk of becoming osteoporotic. The very significant decrease in the use of these treatments is suspected of contributing to a resurgence in the incidence of osteoporotic fractures, particularly in women before the age of 70. There is a need for prevention of osteoporosis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 3 Oct 2022
- Start date
- 12 May 2023
- Primary completion date
- Nov 2027
- Lead sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Diseases
- Osteoporosis
- NCT number
- NCT05571514
What you commit to
- Study type: Interventional
- Planned participants: 200
- From 12 May 2023 to the primary completion date, Nov 2027
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- patients who follow a treatment that could interfere with bone metabolism (corticotherapy, menopausal hormonal therapy, anti-oestrogen treatment, non-controlled hyperthyroiditis, hyper- and hypothyroiditis)
Other illness
- bone diseases (Paget'disease, osteomalacia)
Other
- absence of parathyroid glands (phospho-calcic regulation)
- presence of kidney stones
- chronic alcoholism
Who the study is looking for
- Post-menopausal women (50-65y) with risk of becoming osteoporotic
- T-score between -1 and -3
- Absence of fragility fractures history
Age in the registry: 50 years to 65 years · Sex: Female · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Gabriel Montpied Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Not yet recruiting |
| Clinique Universitaire de Rhumatologie Coordinator of this site? Confirm its status | Grenoble | France | Not yet recruiting |
| CH Emile Roux Coordinator of this site? Confirm its status | Le Puy-en-Velay | France | Not yet recruiting |
| Hopital Edouard Herriot Coordinator of this site? Confirm its status | Lyon | France | Not yet recruiting |
| APHP - Hôpital Cochin Coordinator of this site? Confirm its status | Paris | France | Not yet recruiting |
| CH Roanne Coordinator of this site? Confirm its status | Roanne | France | Not yet recruiting |
| CHU Saint-Etienne Coordinator of this site? Confirm its status | Saint-Etienne | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.