NCT05572632Recruiting
Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Community-based Pulmonary Rehabilitation (COPD Wellness) and Social Navigation (Health Advocates) to Improve Outcomes in Vulnerable Patients With COPD
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
Chronic obstructive pulmonary disease (COPD), one of the leading causes of death in the US, disproportionately affects low socioeconomic communities. While few interventions effectively modify the course of COPD and improve outcomes, pulmonary rehabilitation is the one notable exception. However, implementation of this resource-intensive program in real-life settings, and in particular, for underserved communities, has proven to be challenging. Safety-net centers that serve primarily under-insured populations lack financial resources to provide pulmonary rehabilitation. The 10-week COPD Wellness and Plus+ Program directly addresses this gap, and yet, programs like these do not automatically lead to improved outcomes, which leads to the implementation of a Health Advocates program to address participant's social needs and barriers to healthcare.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 387 (estimated)
- First submitted
- 22 Sept 2022
- Start date
- 19 Jan 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of California, San Francisco
- Diseases
- COPD
- NCT number
- NCT05572632
What you commit to
- Study type: Interventional
- Planned participants: 387
- From 19 Jan 2023 to the primary completion date, 31 Dec 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Dementia, cognitive impairment, or symptomatic psychiatric illness that would impair them from participating
- Unstable cardiovascular disease (includes recent \[\<6 months\] myocardial infarction or pulmonary embolism, uncontrolled arrhythmia, poorly controlled heart failure)
- Transmittable pulmonary infection (tuberculosis, COVID19)
- Other diagnosis or condition that carry a prognosis of death within the next year
Other
- Pregnancy
- Other severe co-morbidity which means exercise is contraindicated (screened by Registered Nurse in consultation with Pulmonologist)
- Participated in pulmonary rehabilitation in the past 12-months
- COPD exacerbation in the past 6 weeks
- Activities restrictions that limit one's ability to engage in moderate physical activity
Who the study is looking for
- Provision of signed and dated informed consent form
- Willingness to participate in the COPD Wellness program
- 40 to 90 years old
- English or Spanish speaking
- Physician-diagnosed COPD
- Spirometry-confirmed FEV1/FVC ratio \<= 0.7 and FEV1% predicted \<80% based on GLI-O prediction equation
- COPD Assessment Test ≥ 10 or history of 1+ exacerbation requiring hospitalization or 2+ outpatient exacerbations requiring steroid therapy
- Currently prescribed COPD medication(s)
- Ability to exercise with lower extremities
- No COPD exacerbations for ≥ 6 weeks
- Currently receiving care within SFHN
- Note: Forced expiratory volume in the first second (FEV1); Forced vital capacity (FVC)
Age in the registry: 40 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Southeast Health Center (SEHC) Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
| Maxine Hall Health Center (MHHC) Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
| Zuckerberg San Francisco General (ZSFG) Hospital Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.