NCT05572801Recruiting
NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer
NOAC9 - A Phase II Randomised Nordic Anal Cancer Group Study on Circulating Tumor DNA Guided Follow-Up
Source: ClinicalTrials.gov · Last updated 14 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study investigates if circulating tumor DNA can improve the detection of early treatment failure or recurrence in localized squamous cell carcinoma of the anus (SCCA) after curative chemoradiotherapy thereby increasing the potential for cure. This will be done by comparing the standard follow-up program with ctDNA guided imaging follow-up. Secondly, the aim is to establish early interventions against late morbidities.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 22 Aug 2022
- Start date
- 2 Aug 2023
- Primary completion date
- 1 Jun 2026
- Lead sponsor
- Aarhus University Hospital
- NCT number
- NCT05572801
What you commit to
- Study type: Interventional
- Planned participants: 400
- From 2 Aug 2023 to the primary completion date, 1 Jun 2026
- 13 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Conditions that will contraindicate blood samples
- Conditions that will contraindicate a PET-CT scan.
Other
- Potential lack of compliance to standard FU program and study participation.
Who the study is looking for
- Patients with SCCA eligible for definitive (chemo)radiotherapy
- ≥ 18 of years
- Written and oral consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (13)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Recruiting |
| Department of Oncology, Herlev and Gentofte Hospital Coordinator of this site? Confirm its status | Herlev | Denmark | Recruiting |
| Department of Oncology, Vejle Hospital Coordinator of this site? Confirm its status | Vejle | Denmark | Recruiting |
| Tampere University Hospital Coordinator of this site? Confirm its status | Tampere | Finland | Not yet recruiting |
| Turku University Hospital Coordinator of this site? Confirm its status | Turku | Finland | Not yet recruiting |
| Haukeland University Hospital Coordinator of this site? Confirm its status | Bergen | Norway | Not yet recruiting |
| Oslo University Hospital Coordinator of this site? Confirm its status | Oslo | Norway | Not yet recruiting |
| University Hospital of North Norway Coordinator of this site? Confirm its status | Tromsø | Norway | Not yet recruiting |
| St. Olav's University Hospital Coordinator of this site? Confirm its status | Trondheim | Norway | Not yet recruiting |
| Sahlgrenska University Hospital Coordinator of this site? Confirm its status | Gothenburg | Sweden | Not yet recruiting |
| Skåne University Hospital Lund Coordinator of this site? Confirm its status | Lund | Sweden | Not yet recruiting |
| Karonlinska University Hospital Coordinator of this site? Confirm its status | Stockholm | Sweden | Not yet recruiting |
| Norrlands University Hospital Coordinator of this site? Confirm its status | Umeå | Sweden | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.