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NCT05572801Recruiting

NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer

NOAC9 - A Phase II Randomised Nordic Anal Cancer Group Study on Circulating Tumor DNA Guided Follow-Up

Source: ClinicalTrials.gov · Last updated 14 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This study investigates if circulating tumor DNA can improve the detection of early treatment failure or recurrence in localized squamous cell carcinoma of the anus (SCCA) after curative chemoradiotherapy thereby increasing the potential for cure. This will be done by comparing the standard follow-up program with ctDNA guided imaging follow-up. Secondly, the aim is to establish early interventions against late morbidities.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
400 (estimated)
First submitted
22 Aug 2022
Start date
2 Aug 2023
Primary completion date
1 Jun 2026
Lead sponsor
Aarhus University Hospital
NCT number
NCT05572801

What you commit to

  • Study type: Interventional
  • Planned participants: 400
  • From 2 Aug 2023 to the primary completion date, 1 Jun 2026
  • 13 sites in 4 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Conditions that will contraindicate blood samples
  • Conditions that will contraindicate a PET-CT scan.

Other

  • Potential lack of compliance to standard FU program and study participation.

Who the study is looking for

  • Patients with SCCA eligible for definitive (chemo)radiotherapy
  • ≥ 18 of years
  • Written and oral consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (13)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Aarhus University Hospital
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AarhusDenmarkRecruiting
Department of Oncology, Herlev and Gentofte Hospital
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HerlevDenmarkRecruiting
Department of Oncology, Vejle Hospital
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VejleDenmarkRecruiting
Tampere University Hospital
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TampereFinlandNot yet recruiting
Turku University Hospital
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TurkuFinlandNot yet recruiting
Haukeland University Hospital
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BergenNorwayNot yet recruiting
Oslo University Hospital
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OsloNorwayNot yet recruiting
University Hospital of North Norway
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TromsøNorwayNot yet recruiting
St. Olav's University Hospital
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TrondheimNorwayNot yet recruiting
Sahlgrenska University Hospital
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GothenburgSwedenNot yet recruiting
Skåne University Hospital Lund
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LundSwedenNot yet recruiting
Karonlinska University Hospital
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StockholmSwedenNot yet recruiting
Norrlands University Hospital
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UmeåSwedenNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.