NCT05576467Completed
Treatment for Migraine and Mood
Treatment for Migraine and Mood (TEAM-M): A Randomized Controlled Trial of a Mindfulness-based Training Program
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
The researchers propose a three-arm pilot study of Mindfulness-Based Cognitive Therapy (MBCT) delivered via telephone (MBCT-T), video (MBCT-V) or Enhanced Usual Care (EUC).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 145 (actual)
- First submitted
- 10 Oct 2022
- Start date
- 17 Mar 2024
- Primary completion date
- 24 Mar 2026
- Lead sponsor
- Amanda Shallcross
- Diseases
- Migraine
- NCT number
- NCT05576467
What you commit to
- Study type: Interventional
- Participants enrolled: 145
- From 17 Mar 2024 to the primary completion date, 24 Mar 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Changes in anti-depressant medication within 6 weeks of intake
- Starting or changing a migraine preventive treatment (i.e., oral medication, injection, preventive medicine, neuromodulatory device) within 12 weeks of intake
- Prior history of engaging in formal mindfulness-based interventions including: MBSR, MBCT, Acceptance and Commitment therapy, Dialectical Behavior Therapy
- Unwilling to maintain stable current acute or preventive medication dosages for study duration
- Medication overuse headache with migraine treatment
Other illness
- Comorbid psychiatric illness or clinical features that would interfere with participant's ability to participate in or receive benefit from the MBCT-T intervention, including but not limited to: active suicidal ideation; current or recent history (in the last six months) of psychosis or mania; borderline, histrionic or narcissistic personality disorder; cognitive impairment; sensory disabilities;, discomfort participating in a group-based intervention, drug use
- Any condition that would prevent being a suitable candidate for the group intervention
Other
- Meeting ICHD-3 criteria for persistent headache attributed to traumatic injury to the head (post- traumatic headache) on the American Migraine Prevalence and Prevention Diagnostic Module
- Changes in acute migraine treatment started within 4 weeks of enrollment
- Current daily meditation practice
Who the study is looking for
- Currently meets ICHD-3 criteria for migraine using the American Migraine Prevalence and Prevention Diagnostic Module
- Self-reported 4-20 headache days per month
- Score between 5-19 on the PHQ-8
- Age ≥ 18
- Ability to read and speak English
- Capacity to consent
- ≥1 year of migraine
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| Albert Einstein College of Medicine Coordinator of this site? Confirm its status | The Bronx | United States | Unknown status |
| Wake Forest University School of Medicine Coordinator of this site? Confirm its status | Winston-Salem | United States | Unknown status |
Related publications
- Evaluating an Abbreviated Version of Mindfulness-Based Cognitive Therapy Delivered via Telephone or Videoconferencing Compared to Enhanced Usual Care-Treatment for Migraine and Mood (TEAM-M) Study: Protocol for a Three-Arm Multisite Randomized Controlled Feasibility Trial.JMIR Res Protoc · 2026 · PMID 42247631
This page is information, not medical advice. Discuss any trial with your doctor.