NCT05577871Completed
Dexmedetomidine in Off Pump Coronary Artery Bypass Grafting
Echocardiographic Evaluation of the Effect of Dexmedetomidine Infusion as an Adjuvant to General Anesthesia in Off-pump Coronary Artery Bypass Grafting
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
the study will assess the impact of intraoperative dexmedetomidine infusion on myocardial performance by investigating the left ventricular (LV) systolic and diastolic function and right ventricular (RV) fraction area change (which reflect RV systolic function) using two-dimensional trans-esophageal echocardiography (TEE) in patients undergoing elective first-time isolated off-pump coronary artery bypass (OPCAB) grafting. LV Systolic function will be measured by the TEE via the fractional area change, fraction shortening, and ejection fraction.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 8 Oct 2022
- Start date
- 1 Nov 2022
- Primary completion date
- 28 Feb 2023
- Lead sponsor
- Suez Canal University
- Diseases
- Coronary artery disease
- NCT number
- NCT05577871
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 1 Nov 2022 to the primary completion date, 28 Feb 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Arrhythmia or received treatment with anti-arrhythmic drugs.
Other illness
- Severe functional liver or kidney disease.
Other
- Diagnosed HF (NYHA class \>3).
- Severe bradycardia (HR \< 45 bpm) and AV block.
- Pathologic esophageal lesion (esophageal stricture or varix )
- Pregnancy.
Who the study is looking for
- Patients undergoing elective first-time off-pump isolated coronary artery bypass graft (OPCAB) surgery
- Patients with good ventricular functions.
- Patients with normal levels of cardiac troponin I and myocardial enzymes
- Patients of Body Mass Index (BMI) more than 20 and less than 34.
Age in the registry: 21 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| faculty of medicine, Suez Canal University Coordinator of this site? Confirm its status | Ismailia | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.