NCT05578300Recruiting
Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific
Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific: a Multicenter, Prospective Registry (ENDURE-APAC)
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
As a major breakthrough of acute stroke treatment over the past decade, endovascular thrombectomy (EVT) drastically improved neurological recovery and survival in patients with large vessel occlusion (LVO) ischemic strokes in major clinical trials. Nevertheless, much remained uncertain about the implementation of scientific evidence of EVT into real-world benefits. For instance, healthcare policies that influence critical time-matrices, endovascular thrombectomy techniques that may enhance success rate or prevent complications, or advanced imaging techniques that allow precise prognosis or expansion of treatment populations, should be evaluated. On the other hand, capturing LVO patients who were not able to undergo EVT may reveal the gap between clinical trials and real-world practice in the Asia-Pacific. In this multicenter prospective collaboration across the Asian-Pacific, the investigators aim to evaluate the determinants of effective EVT in the real-world setting.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 350 (estimated)
- First submitted
- 11 Oct 2022
- Start date
- 21 Oct 2022
- Primary completion date
- 20 Oct 2032
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Stroke
- NCT number
- NCT05578300
What you commit to
- Study type: Observational
- Planned participants: 350
- From 21 Oct 2022 to the primary completion date, 20 Oct 2032
- 3 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patient with isolated vertebral artery occlusion not involving the BA.
Who the study is looking for
- Patient who are over 18 years of age.
- Patient with ischemic stroke with suspected large vessel occlusion (LVO), defined as occlusion of the internal carotid artery (ICA), M1 or M2 segment of the middle cerebral artery (MCA), or basilar artery (BA).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Linyi People's Hospital Coordinator of this site? Confirm its status | Linyi | China | Recruiting |
| The Affiliated Hospital of Medical College of Qingdao University Coordinator of this site? Confirm its status | Qingdao | China | Recruiting |
| Chinese University of Hong Kong Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.