NCT05581212Completed
TB Case-Finding, Treatment and Prevention Intervention in Thailand
Implementation of a New Strategic TB Case-Finding, Treatment and Prevention Public Health Pack in Thailand
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
The project aimed to test a strategy for the early detection and prevention of tuberculosis in household contacts of tuberculosis patients in order to reduce the morbidity, mortality and transmission of this disease in Thailand. This strategy will be evaluated in comparison with the current programmatic approach through a pragmatic trial with cluster randomization (cluster randomized controlled trial) which will be conducted over the next 3 years. This project is carried out in collaboration with the Tuberculosis Division of the Ministry of Public Health of Thailand, the TB/HIV Research Foundation in Thailand and the London School of Hygiene and Tropical Medicine in England.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 7455 (actual)
- First submitted
- 17 Jun 2022
- Start date
- 7 May 2024
- Primary completion date
- 6 Jan 2026
- Lead sponsor
- Institut de Recherche pour le Developpement
- Diseases
- Tuberculosis
- NCT number
- NCT05581212
What you commit to
- Study type: Interventional
- Participants enrolled: 7455
- From 7 May 2024 to the primary completion date, 6 Jan 2026
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Index cases diagnosed with rifampicin resistance, multidrug resistance (MDR) or extensively drug-resistant (XDR-TB)
- Index cases who are incarcerated
- Exclusion of the contacts
- \- contact currently on TPT or on TB treatment or who finished such treatment in the last 3 months.
Other
- Exclusion of index cases
- Index case who do not live in the catchment area of the study cluster
Who the study is looking for
- Inclusion of the index cases
- Age ≥18 years
- Newly bacteriologically confirmed TB case (within 1 month of diagnosis)
- Living in the same household for the last 3 months
- Reporting at least one HH contact
- Providing written informed consent for participation in the study
- Inclusion of contacts
- All contacts living in the same HH, defined as any person who shared the same enclosed living space as the index TB case for one or more nights or for frequent or extended daytime periods for at least one month before the TB diagnosis is made.
- Providing written informed consent (signed by adult (≥18 years) contacts; or by parents/guardians for minors \< 13 years or incapacitated people; written assent for children ≥13 years and \< 18 years).
Sex: All · Accepts healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bang Lamung H. Coordinator of this site? Confirm its status | Bang Lamung | Thailand | Unknown status |
| Nakornping H. Coordinator of this site? Confirm its status | Chiang Mai | Thailand | Unknown status |
| Chiangrai Prachanukroh H. Coordinator of this site? Confirm its status | Chiang Rai | Thailand | Unknown status |
| Chon Buri H. Coordinator of this site? Confirm its status | Chon Buri | Thailand | Unknown status |
| Kalasin H. Coordinator of this site? Confirm its status | Kalasin | Thailand | Unknown status |
| Khon Kaen H. Coordinator of this site? Confirm its status | Khon Kaen | Thailand | Unknown status |
| Lampang H. Coordinator of this site? Confirm its status | Lampang | Thailand | Unknown status |
| Samut Prakan H. Coordinator of this site? Confirm its status | Mueang Samut Prakan | Thailand | Unknown status |
| Buriram H. Coordinator of this site? Confirm its status | Nakhon Ratchasima | Thailand | Unknown status |
| Surin H. Coordinator of this site? Confirm its status | Nakhon Ratchasima | Thailand | Unknown status |
| Maharaj Nakhon Si Thammarat H. Coordinator of this site? Confirm its status | Nakhon Si Thammarat | Thailand | Unknown status |
| Phra Nakhon Si Ayutthaya H. Coordinator of this site? Confirm its status | Phra Nakhon Si Ayutthaya | Thailand | Unknown status |
| Ratchaburi H. Coordinator of this site? Confirm its status | Ratchaburi | Thailand | Unknown status |
| Samut Sakhon H. Coordinator of this site? Confirm its status | Samut Sakhon | Thailand | Unknown status |
| Si Sa Ket H. Coordinator of this site? Confirm its status | Si Sa Ket | Thailand | Unknown status |
| Hat Yai H. Coordinator of this site? Confirm its status | Songkhla | Thailand | Unknown status |
| Songkhla H. Coordinator of this site? Confirm its status | Songkhla | Thailand | Unknown status |
| Surat Thani H. Coordinator of this site? Confirm its status | Surat Thani | Thailand | Unknown status |
| Trang H. Coordinator of this site? Confirm its status | Trang | Thailand | Unknown status |
| Sunpasitthiprasong H. Coordinator of this site? Confirm its status | Ubon Ratchathani | Thailand | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.