NCT05584124RecruitingPhase 2
Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue
Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 7 Oct 2022
- Start date
- 10 Apr 2023
- Primary completion date
- 29 Oct 2027
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Stroke
- NCT number
- NCT05584124
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 60
- From 10 Apr 2023 to the primary completion date, 29 Oct 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Contraindications to magnetic resonance imaging (MRI)/transcranial magnetic stimulation (TMS)/repetitive transcranial magnetic stimulation (rTMS), e.g., implanted metal within the head, history of seizures
- Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate/severe traumatic brain injury (TBI)
- Severe hypertension (resting systolic blood pressure (SBP) \> 200, DBP \> 120)
Other
- Inability to follow simple three-step instructions
- Pregnancy
- Strokes within stimulation sites
- Pregnancy
Who the study is looking for
- More than 6 months post-stroke
- Clinically present fatigue
Age in the registry: 34 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ralph H. Johnson VA Medical Center Coordinator of this site? Confirm its status | Charleston | United States | Not yet recruiting |
| Atlanta VA Medical and Rehab Center, Decatur, GA Coordinator of this site? Confirm its status | Decatur | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.