NCT05584631RecruitingPhase 1
IVIG vs SCIG in CIDP
The Influence of Body Composition on Immunoglobulin Disposition After Intravenous and Subcutaneous Administration
Source: ClinicalTrials.gov · Last updated 11 Dec 2025
Brief summary (registry, in English)
Current dosing practices for immunoglobulin G (IgG) may be inadequate in extreme body weight. The current study will evaluate the influence of body composition on intravenous and subcutaneous administration of immunoglobulin G in patients.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 10 Oct 2022
- Start date
- 11 Sept 2022
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Rutgers, The State University of New Jersey
- NCT number
- NCT05584631
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 20
- From 11 Sept 2022 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving IVIG for indications other than CIDP will be excluded.
Other illness
- Patients with liver impairment (elevations in liver enzymes of greater than 3 times the upper limit of normal) or reduced renal function (CrCl \< 50 mL/min) will be excluded
- Active malignancies
- Diabetes
- Autoimmune disease
Other
- Myasthenia gravis
- Immunodeficiency
Who the study is looking for
- Patients aged \>18 years with a current diagnosis of CIDP (based on European Federation of Neurological sciences / Peripheral Nerve Society CIDP diagnostic criteria).
- 1:1 conversion of IVIG to SCIG (weekly dose conversion) must fall within 0.2-to-0.4 mg/kg dose for SCIG.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rutgers, The State University of New Jersey Clinical Research Center Coordinator of this site? Confirm its status | New Brunswick | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.