NCT05590546Not yet recruiting
Sympathetic Transduction in Obesity
Concomitantly Higher Resting Arterial Blood Pressure and Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension
Source: ClinicalTrials.gov · Last updated 3 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Central (abdominal) obesity is associated with elevated adrenergic activity and arterial blood pressure (BP). Therefore, we tested the hypothesis that transduction of spontaneous muscle sympathetic nerve activity (MSNA) to BP, i.e., sympathetic transduction, is augmented in abdominal obesity (increased waist circumference) and positively related to prevailing BP.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 28 (estimated)
- First submitted
- 18 Oct 2022
- Start date
- 1 Oct 2025
- Primary completion date
- 19 Nov 2026
- Lead sponsor
- University of Kansas Medical Center
- Diseases
- Obesity, High blood pressure
- NCT number
- NCT05590546
What you commit to
- Study type: Observational
- Planned participants: 28
- From 1 Oct 2025 to the primary completion date, 19 Nov 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of anti-hypertensive medications
- history of smoking within 3 months prior to study participation
Other illness
- history of diabetes
- hypertension determined by 24-hour ambulatory average BP (\<130/80 mmHg).
Who the study is looking for
- Nonsmokers
- free of metabolic or neurological disease
- waist circumference \> 102 cm for men and \> 88 cm for women or waist circumference was \< 94 cm for men and \< 80 cm for women.
Age in the registry: 35 years to 65 years · Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.