NCT05595733Completed
Can NAVA Mode Reduce Mechanical Ventilation Day in Patients With COPD ?
Can Neurally Adjusted Ventilatory Assist Mode Reduce Mechanical Ventilation Day in Patients With Chronic Obstructive Pulmonary Disease ?
Source: ClinicalTrials.gov · Last updated 17 Feb 2026
Brief summary (registry, in English)
Background: Neurally Adjusted Ventilatory Assist (NAVA) mode is a new mode of ventilator, using electronic potential of diaphragm to adjust tidal volume. At the same time, this mode can trigger and cycle-off inspiratory time by high sensitivity of electronic potential of diaphragm, increase patient-ventilator synchrony, reduce sedative drug, improve oxygenation, shorten mechanical ventilation day and reduce the rate of diaphragm atrophy. It can improve survival rate and hospital day of patients. Both the animal and human experiment have the effect of lung and diaphragm protection Effect: The results of this trial are expected to obtain electronic potential of diaphragm in patients with obstructive pulmonary disease. Reviewing the current literature, few related literatures have such data presentation. This trial hopes to evaluate whether the use of NAVA can reduce mechanical ventilation day by analyzing electronic potential of diaphragm in patients with obstructive pulmonary disease. Investigators expect that participants with obstructive pulmonary disease using NAVA mode will have significantly less mechanical ventilation day than using conventional mode
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 11 Oct 2022
- Start date
- 1 Nov 2022
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Fu Jen Catholic University Hospital
- Diseases
- COPD
- NCT number
- NCT05595733
What you commit to
- Study type: Interventional
- Participants enrolled: 50
- From 1 Nov 2022 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Those who have received gas cutting
Other illness
- Those who cannot place a nasogastric tube due to medical conditions
- Neuromuscular disease
- Intubation due to cardiac arrest
Other
- Pregnant women
- Patients with phrenic nerve palsy
Who the study is looking for
- Obstructive pulmonary diseases include chronic obstructive pulmonary disease (COPD), asthma (Asthma), cystic fibrosis (cystic fibrosis), bronchiectasis (bronchiectasis), bronchiolitis or other diseases that cause airway stenosis, etc.
- Other patients with obstructive pulmonary disease assessed by the clinical team
- Consent signed by the principal or legal representative
- Age \> 20 years old and \< 99 years old
Age in the registry: 20 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fu Jen Catholic University Hospital All Rights Reserved Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.