NCT05597410Recruiting
Shanghai At Risk for Alzheimer's Disease: a Cohort Study
Source: ClinicalTrials.gov · Last updated 28 Oct 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this cohort study is to estimate the incidence of AD in the first-degree relatives of patients with AD. The main questions it aims to answer are: * cognitive changes of subjects at high risk of AD as ageing; * environmental and behavioral factors affecting AD incidence.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 3418 (estimated)
- First submitted
- 12 Oct 2022
- Start date
- 1 Mar 2022
- Primary completion date
- Mar 2029
- Lead sponsor
- Ruijin Hospital
- Diseases
- Alzheimer disease
- NCT number
- NCT05597410
What you commit to
- Study type: Observational
- Planned participants: 3418
- From 1 Mar 2022 to the primary completion date, Mar 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- other diseases which could cause cognitive decline, e.g. cerebrovascular diseases, Creutzfeldt-Jakob disease and Parkinsons disease;
- history of psychological disorders (according to Diagnostic and Statistical Manual of Mental Disorders, 5th Edition);
- uncorrectable visual or auditory impairment that hampers the completion of related examination.
Other
- Individuals will be excluded if they have:
- pre-menopausal women will also be excluded.
Who the study is looking for
- the AD diagnostic criteria of probands meet the 2011 National Institute on Aging - Alzheimer's Association framework, and participants are the first-degree relatives (including parents, children and siblings of the same father and mother) of the proband;
- not patients with dementia;
- ≥ 50 years, males and females;
- subjects have lived in Shanghai for more than 1 year and have no plan to move out of Shanghai within 5 years;
- subjects are able to complete investigation, physical examination, imaging examination and biological specimen collection.
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.