NCT05598931Completed
Development of Neuro-Navigated Transcranial Magnetic Stimulation (TMS) Using MRI
Source: ClinicalTrials.gov · Last updated 29 Sept 2025
Brief summary (registry, in English)
Healthy controls (HC) will be studied once to provide data needed to validate the virtual neuro-navigation system. All subjects will undergo a single MRI session and will then participate in an on-line neuro-navigation session in which various TMS coil positions will be recorded. The brain/head images will be provided to the programmer to permit development of the virtual neuro-navigation algorithm. Data from Yr1 will be used by the programmer as a training sample, and from Yr2 as a test sample.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 20 (actual)
- First submitted
- 16 Jun 2021
- Start date
- 1 Jul 2021
- Primary completion date
- 1 Oct 2024
- Lead sponsor
- Soterix Medical
- Diseases
- Depression
- NCT number
- NCT05598931
What you commit to
- Study type: Observational
- Participants enrolled: 20
- From 1 Jul 2021 to the primary completion date, 1 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking medications that increase the risk of seizures. For patients on permitted concomitant psychotropic agents (antidepressants, anticonvulsants, benzodiazepines, hypnotics, opiates, triiodothyronine (T3), modafinil, psychostimulants, buspirone, melatonin, omega-3 fatty acids, folate, lmethylfolate, s-adenosyl methionine, lithium) dosing must be stable for at least four weeks prior to study entry
Other illness
- Ever met criteria for a psychotic disorder (Sz, SzAff, Bipolar disorder); anorexia nervosa or bulimia nervosa within the last year
- Recent drug or alcohol use disorder with DSM-5 specifier of moderate or severe within 6 months, or mild within 2 months; lifetime history of IV drug use
- A neurological or neuromuscular disorder;
- Require medications for a general medical condition that contraindicate the TMS treatment
- History of ketamine treatment within 6 mo
- History of monoamine oxidase inhibitor (MAOI) within the past month
Lab values
- Unstable medical condition by history, physical exam or laboratory results
Other
- Contraindications to MRI (based on metal screening form)
- Meets criteria for claustrophobia
- Lacks capacity to consent
Who the study is looking for
- Non-depressed subjects
Age in the registry: 18 years to 60 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Columbia University Irving Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.